NIMTE OpenIR  > 2018专题
Fodis: Software for Protein Unfolding Analysis
Galvanetto, Nicola; Perissinotto, Andrea; Pedroni, Andrea; Torre, Vincent
AbstractThe folding dynamics of proteins at the single-molecule level has been studied with single-molecule force spectroscopy experiments for 20 years, but a common standardized method for the analysis of the collected data and for sharing among the scientific community members is still not available. We have developed a new open-source tool-Fodis-for the analysis of the force-distance curves obtained in single-molecule force spectroscopy experiments, providing almost automatic processing, analysis, and classification of the obtained data. Our method provides also a classification of the possible unfolding pathways and the structural heterogeneity present during the unfolding of proteins.
KeywordMolecule Force Spectroscopy Pathways Mechanics Algorithm Pattern
Subject AreaBiophysics
Document Type期刊论文
Recommended Citation
GB/T 7714
Galvanetto, Nicola,Perissinotto, Andrea,Pedroni, Andrea,et al. Fodis: Software for Protein Unfolding Analysis[J]. BIOPHYSICAL JOURNAL,2018,114(6):1264-1266.
APA Galvanetto, Nicola,Perissinotto, Andrea,Pedroni, Andrea,&Torre, Vincent.(2018).Fodis: Software for Protein Unfolding Analysis.BIOPHYSICAL JOURNAL,114(6),1264-1266.
MLA Galvanetto, Nicola,et al."Fodis: Software for Protein Unfolding Analysis".BIOPHYSICAL JOURNAL 114.6(2018):1264-1266.
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