NIMTE OpenIR  > 2018专题
Highly Sensitive and Selective Potassium Ion Detection Based on Graphene Hall Effect Biosensors
Liu, Xiangqi; Ye, Chen; Li, Xiaoqing; Cui, Naiyuan; Wu, Tianzhun; Du, Shiyu; Wei, Qiuping; Fu, Li; Yin, Jiancheng; Lin, Cheng-Te
2018
Source PublicationMATERIALS
Volume11Issue:3
AbstractPotassium (K+) ion is an important biological substance in the human body and plays a critical role in the maintenance of transmembrane potential and hormone secretion. Several detection techniques, including fluorescent, electrochemical, and electrical methods, have been extensively investigated to selectively recognize K+ ions. In this work, a highly sensitive and selective biosensor based on single-layer graphene has been developed for K+ ion detection under Van der Pauw measurement configuration. With pre-immobilization of guanine-rich DNA on the graphene surface, the graphene devices exhibit a very low limit of detection (approximate to 1 nM) with a dynamic range of 1 nM-10 mu M and excellent K+ ion specificity against other alkali cations, such as Na+ ions. The origin of K+ ion selectivity can be attributed to the fact that the formation of guanine-quadruplexes from guanine-rich DNA has a strong affinity for capturing K+ ions. The graphene-based biosensors with improved sensing performance for K+ ion recognition can be applied to health monitoring and early disease diagnosis.
KeywordG-quadruplex High-quality Dna Aptamers Solar-cells Films Nanoparticles Transistors Recognition Sensor
Subject AreaMaterials Science
Language英语
Document Type期刊论文
Identifierhttp://ir.nimte.ac.cn/handle/174433/16768
Collection2018专题
Recommended Citation
GB/T 7714
Liu, Xiangqi,Ye, Chen,Li, Xiaoqing,et al. Highly Sensitive and Selective Potassium Ion Detection Based on Graphene Hall Effect Biosensors[J]. MATERIALS,2018,11(3).
APA Liu, Xiangqi.,Ye, Chen.,Li, Xiaoqing.,Cui, Naiyuan.,Wu, Tianzhun.,...&Lin, Cheng-Te.(2018).Highly Sensitive and Selective Potassium Ion Detection Based on Graphene Hall Effect Biosensors.MATERIALS,11(3).
MLA Liu, Xiangqi,et al."Highly Sensitive and Selective Potassium Ion Detection Based on Graphene Hall Effect Biosensors".MATERIALS 11.3(2018).
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