NIMTE OpenIR  > 2018专题
Transcellular delivery of messenger RNA payloads by a cationic supramolecular MOF platform
Sun, Peng; Li, Zhen; Wang, Jingyun; Gao, Hui; Yang, Xi; Wu, Sudong; Liu, Deqiang; Chen, Qixian
2018
Source PublicationCHEMICAL COMMUNICATIONS
Volume54Issue:80Pages:11304-11307
AbstractA supramolecular catiomer with a metal-organic framework (MOF) motif was developed to manufacture messenger RNA (mRNA) assemblies. In contrast to the linear catiomer, the dendritic MOF catiomer appeared to markedly improve the colloidal stability of the mRNA assemblies, particularly affording substantial protection to the mRNA payloads from enzymatic degradation, eventually conducing to appreciable mRNA transfection activities at the targeted cells.
KeywordGene Delivery Transfection Polyplexes Polymers Therapy Systems Safe
Subject AreaChemistry ; Materials Science
Language英语
Document Type期刊论文
Identifierhttp://ir.nimte.ac.cn/handle/174433/17127
Collection2018专题
Recommended Citation
GB/T 7714
Sun, Peng,Li, Zhen,Wang, Jingyun,et al. Transcellular delivery of messenger RNA payloads by a cationic supramolecular MOF platform[J]. CHEMICAL COMMUNICATIONS,2018,54(80):11304-11307.
APA Sun, Peng.,Li, Zhen.,Wang, Jingyun.,Gao, Hui.,Yang, Xi.,...&Chen, Qixian.(2018).Transcellular delivery of messenger RNA payloads by a cationic supramolecular MOF platform.CHEMICAL COMMUNICATIONS,54(80),11304-11307.
MLA Sun, Peng,et al."Transcellular delivery of messenger RNA payloads by a cationic supramolecular MOF platform".CHEMICAL COMMUNICATIONS 54.80(2018):11304-11307.
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