NIMTE OpenIR  > 2018专题
Transcellular delivery of messenger RNA payloads by a cationic supramolecular MOF platform
Sun, Peng; Li, Zhen; Wang, Jingyun; Gao, Hui; Yang, Xi; Wu, Sudong; Liu, Deqiang; Chen, Qixian
2018
发表期刊CHEMICAL COMMUNICATIONS
卷号54期号:80页码:11304-11307
摘要A supramolecular catiomer with a metal-organic framework (MOF) motif was developed to manufacture messenger RNA (mRNA) assemblies. In contrast to the linear catiomer, the dendritic MOF catiomer appeared to markedly improve the colloidal stability of the mRNA assemblies, particularly affording substantial protection to the mRNA payloads from enzymatic degradation, eventually conducing to appreciable mRNA transfection activities at the targeted cells.
关键词Gene Delivery Transfection Polyplexes Polymers Therapy Systems Safe
学科领域Chemistry ; Materials Science
语种英语
文献类型期刊论文
条目标识符http://ir.nimte.ac.cn/handle/174433/17127
专题2018专题
推荐引用方式
GB/T 7714
Sun, Peng,Li, Zhen,Wang, Jingyun,et al. Transcellular delivery of messenger RNA payloads by a cationic supramolecular MOF platform[J]. CHEMICAL COMMUNICATIONS,2018,54(80):11304-11307.
APA Sun, Peng.,Li, Zhen.,Wang, Jingyun.,Gao, Hui.,Yang, Xi.,...&Chen, Qixian.(2018).Transcellular delivery of messenger RNA payloads by a cationic supramolecular MOF platform.CHEMICAL COMMUNICATIONS,54(80),11304-11307.
MLA Sun, Peng,et al."Transcellular delivery of messenger RNA payloads by a cationic supramolecular MOF platform".CHEMICAL COMMUNICATIONS 54.80(2018):11304-11307.
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