NIMTE OpenIR  > 2017专题
Synthesis and Vacuum Cold Spray Deposition of Biofunctionalized Nanodiamond/Hydroxyapatite Nanocomposite for Biomedical Applications
Li, Deyan; Chen, Xiuyong; Gong, Yongfeng; Zhang, Botao; Liu, Yi; Jin, Peipeng; Li, Hua
2017
Source PublicationADVANCED ENGINEERING MATERIALS
Volume19Issue:12
AbstractInsufficient biological performances of titanium alloys have been the long-standing problems for their clinical applications. Here, we report synthesis of novel hydroxyapatite/nanodiamond-bone morphogenetic protein 2 (HA-ND/BMP2) composite powder and their coatings deposited by vacuum cold spray operated at room temperature. The microstructure and chemistry of the HA-ND/BMP2 powder and coatings are characterized by transmission electron microscopy, field-emission scanning electron microscopy, thin-film X-ray diffraction, Raman spectrometry, and X-ray photoelectron spectroscopy. In vitro growth assay of osteoblasts on the coatings showed that the biofunctionalized nanodiamonds promoted cell adhesion and proliferation. This study provides a promising technical route for constructing biofunctionalized nanocomposites coatings for potential biomedical applications.
KeywordBone Morphogenetic Protein-2 Mesenchymal Stem-cells Drug-delivery Systems Nanodiamond Coatings Composite Titanium Biocompatibility Differentiation Microstructure
Subject AreaPolymer Science
Language英语
Document Type期刊论文
Identifierhttp://ir.nimte.ac.cn/handle/174433/17495
Collection2017专题
Recommended Citation
GB/T 7714
Li, Deyan,Chen, Xiuyong,Gong, Yongfeng,et al. Synthesis and Vacuum Cold Spray Deposition of Biofunctionalized Nanodiamond/Hydroxyapatite Nanocomposite for Biomedical Applications[J]. ADVANCED ENGINEERING MATERIALS,2017,19(12).
APA Li, Deyan.,Chen, Xiuyong.,Gong, Yongfeng.,Zhang, Botao.,Liu, Yi.,...&Li, Hua.(2017).Synthesis and Vacuum Cold Spray Deposition of Biofunctionalized Nanodiamond/Hydroxyapatite Nanocomposite for Biomedical Applications.ADVANCED ENGINEERING MATERIALS,19(12).
MLA Li, Deyan,et al."Synthesis and Vacuum Cold Spray Deposition of Biofunctionalized Nanodiamond/Hydroxyapatite Nanocomposite for Biomedical Applications".ADVANCED ENGINEERING MATERIALS 19.12(2017).
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